Inauen R, Koch D, Bass M.
Read More >>
Arthrodesis of the tarsometatarsal joints in a cat with a two hole advanced locking plate system.
Koch&Bass Referal Practice for Small Animal Surgery, Basadingerstrasse 26, 8253 Diessenhofen, Switzerland. rinauen@kochbass.ch
2009
This report describes the successful use of the novel fixed-angle locking plating system ALPS (advanced locking plate system) in the case of dorsal tarsometatarsal instability in a cat. Partial arthrodesis of the tarsometatarsal joint was performed with a two hole ALPS 5 and two 2.4 mm selftapping locking screws through a small dorsal approach. Five days after the surgery…
Schlegel U, Perren SM.
Read More >>
Surgical aspects of infection involving osteosynthesis implants: implant design and resistance to local infection.
AO Research Institute, AO Foundation, Davos, Switzerland.
May 2006
Infection is still a major complication associated with surgery in orthopedics and traumatology. The implant design, the implant material, and the implantation technique may play essential roles in preventing infection. The goal of this paper is to discuss a series of experiments evaluating different aspects of both surgical…
Perren SM.
Read More >>
Backgrounds of the technology of internal fixators.
AO Research Institute, Davos, Switzerland.
November 2003
PMID: 14580979 [PubMed - indexed for MEDLINE]
Perren SM.
Read More >>
Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biology.
AO Research and Development Institutes, Davos, Switzerland.
November 2002
The advent of ‘biological internal fixation’ is an important development in the surgical management of fractures. Locked nailing has demonstrated that flexible fixation without precise reduction results in reliable healing. While external fixators are mainly used today to provide temporary fixation in fractures after severe injury, the internal…
Eijer H, Hauke C, Arens S, Printzen G, Schlegel U, Perren SM.
Read More >>
PC-Fix and local infection resistance–influence of implant design on postoperative infection development, clinical and experimental results.
Department of Orthopaedic Surgery, University Hospital Amsterdam, The Netherlands.
September 2001
Bacterial infection is still one of the main complications after internal fixation of fractures. The design of implants influences local infection resistance. To reduce the development of infections around implants after internal fixation, the vitality of the bone should be preserved to optimize cellular and humoral host defense…
Hertel R, Eijer H, Meisser A, Hauke C, Perren SM.
Read More >>
Biomechanical and biological considerations relating to the clinical use of the Point Contact-Fixator–evaluation of the device handling test in the treatment of diaphyseal fractures of the radius and/or ulna.
Department of Orthopaedic Surgery, Inselspitel, University Berne, Switzerland.
September 2001
The Point Contact-Fixator (PC-Fix) was designed as part of the developmental evolution of more biological devices for internal fixations. It is a device characterized by minimal contact to the underlying periosteum and bone, hereby minimizing potential damage to perfusion. A multicentre handling test was conducted in 1993 and 1994 in six hospitals to assess its performance. A total of 83 fractured forearm bones (34 radii and 49 ulnae) in…
Haas N, Hauke C, Schütz M, Kääb M, Perren SM.
Read More >>
Treatment of diaphyseal fractures of the forearm using the Point Contact Fixator (PC-Fix): results of 387 fractures of a prospective multicentric study (PC-Fix II).
Clinic for Trauma and Reconstructive Surgery, Charité, Humboldt University, Berlin, Germany.
September 2001
Fractures of the forearm are considered to be a very good indication for plating. Conventional plating is still technically demanding. Extensive animal studies show that there is potential for improvement. The method consists of using an internal fixator that minimizes implant contact to the bone to reduce biological damage. Furthermore, foregoing the need for precise reduction and interfragmental compression…
Arens S, Eijer H, Schlegel U, Printzen G, Perren SM, Hansis M.
Read More >>
Influence of the design for fixation implants on local infection: experimental study of dynamic compression plates versus point contact fixators in rabbits.
OBJECTIVES: Comparison of infection resistance after local bacterial challenge associated with two different designs for fixation implants: the conventional dynamic compression plate (DCP) and the point contact fixator (PC-Fix). DESIGN: Randomized, prospective study in experimental animals. Grouped sequential experimental procedure. Observation time was twenty-eight days, with twenty animals per…
Fernández Dell'Oca AA, Tepic S, Frigg R, Meisser A, Haas N, Perren SM.
Read More >>
Treating forearm fractures using an internal fixator: a prospective study.
British Hospital, Montevideo, Uruguay.
August 2001
Some major complications of internal fixation with plates, such as infections and disturbance of healing, have been shown to be related to necrosis of bone and to the soft tissues immediately deep to the plate. This is attributable to plate contact. To deal with this phenomenon, an internal fixator, the Point Contact Fixator, was developed according to a new concept. The Point Contact Fixator resembles a plate but…
Hauke C, Meisser A, Perren SM.
Read More >>
Methodology of clinical trials focusing on the PC-Fix clinical trials.
Once development and mechanical and biological laboratory testing have been completed, new technologies to be used in orthopaedic and trauma surgery must be investigated in humans before they can be used routinely. Prospective clinical investigations with or without randomization to standard treatments conducted according…
